Azulfidine - a medicine with antimicrobic and antiinflammatory properties. It is taken at ulcer colitis, an ulcer proctitis, a pseudorheumatism, Crohn's disease. After reception Sulfasalazinum - it is observed the normal intestinal microflora, and as result of the molecule of active ingredient breaks up to compound components: sulphapyridine and 5-aminosalicylic acid. These substances have antibacterial and antiinflammatory activity. Antiinflammatory effect of 5-aminosalicylic acid thanks to low ability to absorption is defined generally in walls of a large intestine. Sulphapyridine has generally systemic antiinflammatory effect due to better absorption.
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Azulfidine Product Description
Azulfidine is an anti-inflammatory drug with a strong immunomodulating activity. Azulfidine is effective in treatment of rheumatic diseases and bowel inflammation in children aged 6 years and older and adults.
Azulfidine pills can be indicated for:
treatment of active Crohn's Disease;
induction and prolongation of the remission of mild, moderate, or severe ulcerative colitis;
treatment of polyarticular juvenile rheumatoid arthritis;
treatment of active rheumatoid arthritis in adults, when first-line treatment with non-steroidal anti-inflammatory drugs (including salicylates) has failed.
If you miss a dose of the anti-inflammatory drug, take Azulfidine pills when you remember it, but not if it is the time to take the next scheduled dose. Never take a double dose of Azulfidine.
If you miss the evening dose, take Azulfidine pills immediately after waking up. However, if you remembered about the missed evening dose when you have to take the morning dose, do not double an Azulfidine dose, just return to the prescribed dosage regimen.
Azulfidine can be used as adjuvant therapy combined with corticosteroids and dietary measures in acute attacks and relapse of ulcerative colitis. Azulfidine significantly improves joint mobility in 4-8 weeks after starting application.
Therefore, in the first few months of Azulfidine use, NSAIDs and /or analgesics can be indicated to the patient to maintain the anti-arthritic effect and relieve arthritis pain.
To protect Azulfidine tablets from light and moisture, they are recommended to be kept in a dry place, in original package, at temperature not below 15°C.
Azulfidine Safety Information
Azulfidine use should be stopped if the patient during the anti-inflammatory therapy experiences symptoms of or have been diagnosed with kidney abnormalities, liver diseases, hematological disorders, infectious diseases, or severe allergies. For early diagnosis of potential risk factors in the first months of Azulfidine use, the patients may be advised to periodically undergo blood tests, urinalysis, and other laboratory and diagnostic tests.
Information about Azulfidine is provided for informational purposes only and not intended to substitute the consultation with the gastroenterologist and/or rheumatologist. The online pharmacy shall assume no responsibility for any loss, omissions, or damage caused by as a result of using the information about this anti-inflammatory and immunomodulating drug.
Azulfidine Side Effects
Azulfidine may cause loss of appetite, fatigue and nausea in the first days of the inflammatory therapy. The long-term application of Azulfidine may cause weight loss, headache, or vomiting in about 30% of patients.
Some men may complain of the decreased ejaculate volume because of Azulfidine use. Approximately 3% of patients, after Azulfidine intake, may experience allergy and haematological disorders. High daily doses of Azulfidine are most likely to cause adverse gastrointestinal effects comparing to minimal maintenance doses of Azulfidine.
If initial doses of Azulfidine cause serious gastrointestinal effects, the patient is recommended:
- To stop taking Azulfidine pills (resume them within 5-7 days after withdrawal).
- To cut the daily dose of Azulfidine in half (followed by gradual increase in the dose within 2-3 days).
- To switch ordinary Azulfidine pills to Azulfidine EN-tabs (medications with sustained-release active ingredient).