Being a part of the medicine Allegra - fexofenadine it is an antihistamine with a selective antagonistic activity to H1-receptors without anticholinergic and blocking alfa1-adrenergic receptors; also at fexofenadine isn't observed a sedative action and other effects from the central nervous system. The antihistaminic effect of Allegra is observed in 1 hour, reaching its maximum in 6 hours, and proceeds within 24 hours. After 28 days of taking the medicine there wasn't observed the accustoming to it.
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Allegra product description
Allegra is a third-generation antihistamine drug, prescribed to adults and children aged 6 years and older to relieve symptoms, caused by:
- seasonal allergic rhinitis
- perennial allergic rhinitis
- chronic idiopathic urticaria
Allegra prevents and suppresses the effect of biologically active histamine that affects the receptors of respiratory system, skin and eyes, and causes allergy symptoms.
Allegra safely and effectively eliminates rhinorrhea, sneezing, red eyes, itchy nose, palate, throat; reduces pruritus, and the number of weals. A characteristic feature of Allegra is that this drug has no sedative effect, and does not affect the psychomotor activity.
The recommended dose of Allegra for children of 6 to 11 years (inclusive) is 30mg, twice a day. The recommended Allegra dose for adults and adolescents of 12 years of age and older is 60mg, twice a day (every 12 hours). Adult patients can sometimes be prescribed once-daily dose of Allegra 180 mg.
Clinical studies showed that one missed dose of Allegra had no clinically significant effect on the treatment of an allergic condition. However, the patients are advised to adhere to the dosing regimen and to take Allegra doses in a timely manner. Do not take the missed Allegra dose, if the next dose should be taken in a while (less than 5 hours).
Based on the pharmacodynamic profile and the known side effects, it can be concluded that Allegra does not affect the ability to operate a vehicle and perform attention-requiring tasks.
During the researches, it was found that Allegra had no significant effect on the central nervous system function, however the individual drug response is recommended to be evaluated before proceeding with a vehicle operation.
Allegra drug should be protected from excessive moisture, so it should be stored in a dry place, at temperature no higher than 30°C. No other special storage conditions for Allegra are required.
Allegra safety information
Elderly patients and hepatically or renally impaired patients do not require correction of the daily Allegra doses. The risk of side effects is higher in patients with renal insufficiency, than in patients with normal renal function. Before you start antiallergic therapy during pregnancy, you should carefully weigh the potential benefits and risks of Allegra to the fetus.
Allegra is not biotransformed in the liver, so it does not interact with other drugs that are metabolized by the liver. The patients are recommended to observe an interval of at least two hours between the intake of Allegra and drugs for stomach acidity neutralization.
Published information about the antihistamine Allegra should not be considered as a substitute for the healthcare practitioner’s professional advice or recommendation. The online pharmacy makes no representations or warranties in relation to the completeness or accuracy of the information about anti-allergy medication Allegra.
Allegra side effects
Allegra causes serious adverse reactions very rarely. Less than 4% of the patients, taking part in clinical trials of Allegra, stopped the antiallergic therapy because of side effects.
Approximately 3% of patients, using Allegra for the treatment of seasonal allergies, can have headache. Other side effects occur in less than 2% of patients. It should be noted that Allegra may cause different adverse reactions in different age groups.
- For example, after the use of Allegra, adults may feel drowsiness, earache, thirst, dizziness, dyspepsia, diarrhea, nausea, fatigue.
- In children, Allegra may promote an increased risk of upper respiratory tract infection, as well as fever and coughing.
The severity and frequency of side effects depend on the Allegra dose used. Side effects manifest more often, when Allegra is used to control symptoms of chronic allergies, than in the symptomatic treatment of seasonal allergies.