Cipro - the antimicrobic broad-spectrum agent derivative of fluroquinolone, suppresses bacterial DNA gyrase, breaks DNA synthesis, growth and division of bacteria; causes prominent morphological changes and fast death of a bacterial cell. It effects bactericidal at gram-negative organisms during a dormant period and deletion, on gram-positive microorganisms - only during deletion. During taking Cipro there is no parallel development of resistance to other antibiotics, which do not belong to group of inhibitors of a gyrase that does it highly effective in relation to bacteria which can be steady, for example to aminoglycosides, penicillin, cephalosporins, tetracyclines and many other antibiotics.
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Cipro Product Description
Cipro is an antimicrobial drug that has a broad-spectrum antibacterial action. This antibiotic is effective against most gram-positive and gram-negative aerobic bacteria. Cipro exerts a bactericidal effect on the microbial cell both at rest and during its growth. Bacterial resistance to the antibiotic develops slowly, largely during gene mutation, which reduces the permeability of the cell membrane of microorganism.
Cipro antibiotic is prescribed for children, adults and elderly patients for the treatment of:
urinary tract infections
bone and joint infections
upper respiratory tract infections
lower respiratory tract infections
skin and skin structure infections
The maximum concentration of the antibiotic in the blood is reached within 1-1.5 hours when taken orally. Food intake does not almost affect the antibiotic absorption and its bioavailability.
Cipro dose is matched individually taking into account the type of infection, the patient’s tolerance and individual characteristics. The duration of infection treatment depends on the disease severity and bacteriological response.
A single doses of Cipro antibiotic for adults vary from 250 to 750 mg. A pediatric dose of Cipro antibiotic is calculated according to the child's body weight. Commonly, dosage for children varies from 10 to 20 mg of the antibiotic per each kg of body weight.
If you forget to take a scheduled dose of Cipro, take the missed dose as soon as you remember. If it is almost time for the regular dose of the antibiotic, skip the missed dose of Cipro and take this antibiotic according to the dosage schedule. Do not take a double dose of Cipro to make up the missed one.
Due to the fact that gram-positive anaerobic bacteria streptococcus pneumoniae is not sensitive to the antibacterial effect of Cipro, this antibiotic should not be used to treat pneumococcal infections.
During Cipro use, patients are advised to drink plenty of fluids to reduce the risk of crystalluria. Prolonged and repeated antibiotic therapy can lead to the growth of resistant bacteria to Cipro and fungal infections.
Cipro antibiotic must be kept in a dry warm place, out of children's reach, at temperature not above 30°C.
Cipro Safety Information
Clinical studies have shown that Cipro use increases the risk of tendinitis and tendon rupture in patients of all ages. Patients with Achilles tendon are more prone to this side effect. Cipro antibacterial drug may contribute to severe hepatotoxicity, including liver necrosis. At the first symptoms of hepatitis, the patients are recommended to stop using Cipro and start the appropriate therapy.
This Cipro review contains familiarization material about antibiotic therapy. Information about Cipro is in no way a substitute for the professional advice provided by a health care provider specializing in the treatment of bacterial infections. The online pharmacy provided this information cannot be held responsible for any consequences, damages and errors, indirect or direct connected with the use of the information contained in this review of Cipro antimicrobial agent.
Cipro Side Effects
Cipro is a safe antibiotic, which is well tolerated. In treatment with Cipro, the most common adverse reactions are: nausea, diarrhea, vomiting and rash. When using Cipro, the pediatric patients aged 1 year to 17 years may experience indigestion, fever and asthma. The adults experience these adverse reactions less frequently than children and adolescents do.
Rarely, adverse reactions of Cipro include loss of appetite, digestive disorders, abdominal pain, flatulence, tiredness, dizziness, headache, tremor, confusion, pruritus, and drug fever. Cipro research results have demonstrated that the cessation of antibiotic therapy is required to approximately 5% of patients because of serious adverse reactions.