Celebrex - non-steroidal anti-inflammatory drug. It has antiinflammatory, febrifugal and analgesic effect, slows down aggregation of thrombocytes. Oppressing COX-2, reduces quantity of Pg (preferentialy in the inflammation center), suppresses exudative and proliferative phases of inflammation. At prescribtion in high doses, prolonged use or specific features of an organism the selectivity decreases.
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Celebrex Product Description
Celebrex is a nonsteroidal anti-inflammatory agent used for the symptomatic treatment of inflammatory joint diseases (IJD), as well as for pain relief of various intensity and localization. Celebrex effectively relieves pain and joint inflammation in patients with:
- degenerative rheumatic diseases (including osteoarthritis);
- juvenile rheumatoid arthritis (including systemic, polyarticular and pauciarticular types);
- autoimmune rheumatic diseases (including rheumatoid arthritis, and ankylosing spondylitis).
For relief of the symptoms of rheumatic diseases in children younger than two years and adults, the maintenance doses of Celebrex vary from 100mg to 200mg per day. For the management of severe rheumatoid arthritis flare-ups, the maximum daily dose of Celebrex 400mg can be prescribed.
Due to the fact that Celebrex capsules exert not only anti-inflammatory, but also a powerful analgesic effect, they can be used to relieve acute pain caused by:
- tooth extraction;
- trauma and sprains;
- orthopedic surgery.
Women can use Celebrex capsules for management of acute pain episodes caused by primary dysmenorrhea. To treat pain syndromes in adult men and women, the maximum daily dose of Celebrex is 400mg divided into two equal doses.
If you use Celebrex on a schedule and forgot to take a regular dose, take the missed dose of this anti-inflammatory drug as soon as you remember. If it is almost time for the next dose of Celebrex, skip the missed dose of this drug and continue your regular dosing schedule.
- If Celebrex capsules are used as an analgesic agent, the duration of their use should not exceed 7 days in a row.
- The duration of Celebrex use for the symptomatic treatment of rheumatic diseases is prescribed individually for each patient.
- Patients with chronic rheumatic conditions may require a symptomatic treatment of joint disease lasting from several months to several years.
Celebrex capsules should be stored at room temperature of up to 25°C. Storage and transportation of Celebrex capsules may be at temperature of up to 30°C. This anti-inflammatory / analgesic agent should be kept out of sight and reach of children and pets.
Celebrex Safety Information
In prolonged use of Celebrex and while using high doses of this drug, a risk of gastrointestinal bleeding, hypertension, cardiovascular and cerebrovascular events may increase. Smoking, alcohol use, elderly age, and Celebrex combination with other drugs are potential factors for increasing the risk of serious gastrointestinal and / or cardiovascular effects.
The information contained in this Celebrex review is published for informational purposes only and not intended as a substitute for services provided by a rheumatologist, gynecologist, surgeon or other medical professionals. The online pharmacy is not liable for any damage of a material or immaterial nature ensuing from the use or non-use of information about the analgesic / anti-inflammatory therapy provided in Celebrex review.
Celebrex Side Effects
During clinical trials of Celebrex capsules, it was noted that elderly people aged 75 and older experienced unwanted effects more frequently than patients of other age groups did. However, regardless of the patient’s age and the used Celebrex dose, this anti-inflammatory drug rarely causes serious unwanted effects. Celebrex may increase the risk of hypertension, sinusitis, dizziness, pharyngitis, flatulence, diarrhea, rhinitis, rash or peripheral edema in some patients.
The most common reasons for Celebrex cancellation because of unwanted effects are abdominal pain and dyspepsia. These unwanted effects do not occur or are mild in the majority of patients with rheumatic diseases.